MECHANISM OF ACTION OF A NEW ANTI-INFLAMMATORY AGENT, NAPROXEN (II)
نویسندگان
چکیده
منابع مشابه
Mechanism of action of a new antitumor agent, carbetimer.
Carbetimer, an intermediate molecular-weight-derivatized copolymer of maleic anhydride and ethylene, has been shown to possess significant antineoplastic activity in the stem cell assay. We have examined the antitumor activity of carbetimer in vivo and in vitro against HM5-Carb/S and M21, both primary human melanoma cell lines sensitive and resistant to carbetimer, respectively. The mechanism o...
متن کاملMechanism of Action of a New Antitumor Agent, Carbetimer1
Carbetimer, an intermediate molecular-weight-derivatized copolymer of maleic anhydride and ethylene, has been shown to possess significant antineoplastic activity in the stem cell assay. We have examined the antitumor activity of carbetimer in vivo and in vitro against HMS-Carb/ S and M21, both primary human melanoma cell lines sensitive and resistant to carbetimer, respectively. The mechanism ...
متن کاملA New Antiepileptic Agent with Novel Mechanism of Action
Epilepsy is one of the most common neurological disorders estimated to affect about 1% of the general population [1]. Until 1992, there were 4 main antiepileptic medications primarily utilized for the treatment of epilepsy and they included phenobarbital, phenytoin, carbamazepine, and valproic acid. After 1992, there was an explosion of medications approved for the treatment of seizures. The mo...
متن کاملToward a new anti-inflammatory and analgesic agent.
I a comparative study on normal and B1-receptor deficient (B1-KO) mice, Pesquero et al. (1) provide evidence in this issue of PNAS in favor of crucial roles played by the kinin B1 receptor in toxic shock, inflammation, and nociception. B1 receptors are generally silent or absent in healthy states and are induced or activated by pathological challenges. When they are absent, as in B1-KO mice, ti...
متن کاملAnti-inflammatory action of corticosteroids.
The anti-inflammatory action of corticosteroids is complex. At a cellular level, they cause redistribution of granulocytes, resulting in increased circulating granulocytes and reduced tissue pools. They also cause lymphopenia. The significance of these phenomena in relation to the anti-inflammatory activity of steroids is unknown. The most obvious pharmacological effects of corticosteroids are ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1976
ISSN: 0021-5198
DOI: 10.1254/jjp.26.91